Bant Breen:
Eric, you have an incredible background, working in the pharma space and as a researcher on the academic level, as well as an entrepreneur. Tell me a little bit more about what your hope is and why it’s important in the medical profession today.
Eric Fossel:
Odin is based on a finding that I published 26 years ago a unique way of killing cancer cells. In 1994, when it was published, all we knew is we killed the cancer cells, we didn’t understand how or what the implication was. Over the last 2627 years, immuno-oncology and even immunology have progressed to a point where we now understand what we published in 2009-2094. That is the way we make the cancer cell kill itself from the inside out, signal to the rest of the body that it’s a cancer cell, and come and eat me take it and activate the immune system. Then vaccinate the body against further reoccurrence of cancer and when we realized how that worked, we realized that could also be applied to vaccines. The mRNA vaccines that are being successful now and the vaccines that have been produced for the last nearly 100 years all are approached by very different methodologies. We short circuit most of those and jump right into the key thing that those vaccines are peripherally trying to make happen which is to make the T and B cells make antibodies and killer T cells. So we bypass a lot of the machinery of other vaccines.
Bant Breen:
Tell me a little bit more about your other business.
Eric Fossel:
Novilla is based on something I discovered some 20 years ago that was a way to get drugs across the skin to raise the free energy or make them unhappy in their environments. We put them into a cream or a lotion where they’re unhappy and we do that currently by putting them in what’s called an ionic liquid her deep eutectic solvents We used to do it with just plain salt, truly sodium chloride. Now we do it with something much more sophisticated and effective. It drives most drugs through the skin, you might know about how patches work. Things like nicotine and estrogen, things that have no charge. Most drugs are charged, and won’t go through the skin unless you do something like what we do. That opens up a whole new category of things on Novilla. The first project and what attracted me to come to work with Novilla and license some of my technology to them was that they had the idea that if you could put a strong thing for anti-inflammatory, called fetoscopy, through the screen above the spine. Where the nerve from the pain comes into the spine, you can intercept it on its way to the brain and cause the pain not to be felt. That’s important in many settings. We’re the most important one is post-surgical pain where people are exposed to opioids, and often get addicted to opioids. This red pill result of their pain therapy after surgery. So the first drug is positioned to replace opiates and post-surgical pain.
Bant Breen:
What are your thoughts on all of these new vaccines that are coming out for COVID?
Eric Fossel:
I’m amazed at how well mRNA vaccines work. That’s a new concept that has never been done before. They did it so quickly and they’re so effective. I was expecting to look at around 50% efficacy. I was pleasantly surprised to see them in the 90s. They have problems that have to be kept cold, they have a short shelf life, they’re complicated to make, and probably will never be available in the third world. The approach we’re taking to vaccines doesn’t have many of those problems and doesn’t have to be refrigerated at all. Doesn’t even have to be administered through a needle. There are 30% of the people in this country and more than the rest of the world that hate needles and probably won’t get the vaccine because of that. Having a nonrefrigerated, needle-free vaccine, would be extraordinary.
Bant Breen:
Eric, thank you so much for being on UNCAGED today and we look forward to having you back.
To see the full interview on the Uncaged YouTube channel, go to:
